货号：MAB4372

品牌：Merck Millipore

规格：100Ug

目录价：￥4502.00

市场价格：￥3826.70

会员价格：￥3601.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-ID-1 Antibody, clone 7D4.2 | MAB4372 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Immunogen: Recombinant ID-1 protein View All» Clone: 7D4.2 View All» Isotype: IgG1 View All» Background Information: Id-1 is an inhibitor of differentiation protein, which, along with Id2, Id3 and Id4, plays a key role in the regulation of lineage commitment, cell fate decisions and in the timing of differentiation during neurogenesis, lymphopoiesis and neovascularisation (angiogenesis). Id proteins, induced by the bone morphogenic protein-SMAD pathway, have also been shown to collaborate with LIF to ensure that embryonic stem cells opt for self-renewal. View All» Species Reactivity:

• Human

• Mouse
  View All» Presentation: Supplied in PBS Buffer, pH 7.0 with 0.1% sodium azide View All» Storage Conditions: Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. View All» UniProt Number: P41134 View All» Entrez Gene Number:
  • NM_002165.2

  • NM_181353.1
    View All» Gene Symbol:
    • ID1

    • ID
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Multiplexing

      • Immunofluorescence

      • Western Blotting
        View All» Entrez Gene Summary: The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P41134 # ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding.SIZE: 155 amino acids; 16133 Da SUBUNIT: Heterodimer with other HLH proteins. Interacts with COPS5 (By similarity).SUBCELLULAR LOCATION: Nucleus.DEVELOPMENTAL STAGE: Expression correlates with proliferation in some types of cells.SIMILARITY: SwissProt: P41134 ## Contains 1 basic helix-loop-helix (bHLH) domain. View All» Brand Family: Chemicon View All» Product Name: Anti-ID-1 Antibody, clone 7D4.2 | MAB4372 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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