货号：MAB4353

品牌：Merck Millipore

规格：

目录价：￥3662.00

市场价格：￥3112.70

会员价格：￥2929.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Id3 Antibody, clone 3F2 | MAB4353 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Immunogen: Recombinant GST Fusion protein (Human Id-3). View All» Clone: 3F2 View All» Isotype: IgG1 View All» Background Information: Id-3 is an inhibitor of differentiation protein, which, along with Id1, Id2 and Id4, plays a key role in the regulation of lineage commitment, cell fate decisions and in the timing of differentiation during neurogenesis, lymphopoiesis and neovascularisation (angiogenesis). Id proteins, induced by the bone morphogenic protein-SMAD pathway, have also been shown to collaborate with LIF to ensure that embryonic stem cells opt for self-renewal. View All» Species Reactivity: Mouse View All» Presentation: Liquid in PBS, pH 7.0. Contains 0.1% sodium azide. View All» Storage Conditions: Maintain refrigerated at 2-8C in undiluted aliquots for up to 12 months. View All» UniProt Number: Q02535 View All» Entrez Gene Number: NM_002167.3 View All» Gene Symbol:

• ID3

• 1R21

• HEIR-1
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Immunocytochemistry
    View All» Entrez Gene Summary: Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: Q02535 # ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors.SIZE: 119 amino acids; 12969 Da SUBUNIT: Interacts with COPS5 and COPS7A (By similarity). Homodimer, and heterodimer with other HLH proteins.SUBCELLULAR LOCATION: Nucleus.TISSUE SPECIFICITY: Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain.SIMILARITY: SwissProt: Q02535 ## Contains 1 basic helix-loop-helix (bHLH) domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Id3 Antibody, clone 3F2 | MAB4353 View All» Concentration: 1 mg/ml View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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