货号：04-253

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-19S regulator ATPase subunit S6a/Rpt5 Antibody, clone TBP1-19 | 04-253 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes 19S regulator ATPase subunit S6a/Rpt5. View All» Molecular Weight: 49 kDa View All» Immunogen: Full length human recombinant Rpt5 protein. View All» Clone: TBP1-19 View All» Isotype: IgG2b View All» Species Reactivity:

• Human

• Mouse

• Rat

• Rabbit
  View All» Purification Method: Ascites View All» Presentation: 100 µL of purified from ascites containing 0.01M sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4. View All» Storage Conditions: Stable for 1 year at -20°C from date of shipment for up to 12 months. View All» UniProt Number: P43686 View All» Entrez Gene Number:
  • NM_006503.2

  • NM_153001.1
    View All» Gene Symbol:
    • PSMC4

    • MGC23214

    • MGC13687

    • TBP-7

    • MGC8570

    • MIP224

    • TBP7

    • S6
      View All» Alternate Names: 26S proteasome ATPase subunit 4; S6a View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Entrez Gene Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with an orphan member of the nuclear hormone receptor superfamily highly expressed in liver, and with gankyrin, a liver oncoprotein. Two transcript variants encoding different isoforms have been identified. View All» UniProt Summary: FUNCTION: SwissProt: P43686 # The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.SIZE: 418 amino acids; 47366 Da SUBUNIT: Interacts with NR1I3. Interacts with PAAF1.SUBCELLULAR LOCATION: Cytoplasm. Nucleus.PTM: The N-terminus is blocked.SIMILARITY: SwissProt: P43686 ## Belongs to the AAA ATPase family. View All» Brand Family: Upstate View All» Product Name: Anti-19S regulator ATPase subunit S6a/Rpt5 Antibody, clone TBP1-19 | 04-253 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Mouse View All»
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