货号：MAB425

品牌：Merck Millipore

规格：500Ug

目录价：￥4099.00

市场价格：￥3484.15

会员价格：￥3279.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Carcinoembryonic Antigen Antibody, clone 1105 | MAB425 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Human Carcinoembryonic Antigen (CEA) View All» Immunogen: Purified CEA from pooled tumors. View All» Clone: 1105 View All» Isotype: IgG1 View All» Species Reactivity: Human View All» Application Notes: Sandwich RIA or EIA Optimal working dilutions must be determined by the end user. View All» Presentation: Purified immunoglobulin (Protein A). Liquid in PBS, pH 7.4 containing 0.1% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store below -20°C or in dry ice as precipitation will occur. View All» UniProt Number: P13688 View All» Entrez Gene Number:

• NM_001024912.1

• NM_001712.3
  View All» Gene Symbol:
  • CEACAM1

  • BGP-1

  • BGP1

  • BGP

  • CD66a

  • BGPI
    View All» Alternate Names: CEA; CD66e View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Radioimmunoassay
      View All» Entrez Gene Summary: This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined. View All» UniProt Summary: SIZE: 526 amino acids; 57560 Da SUBCELLULAR LOCATION: Isoform A: Cell membrane; Single-pass type I membrane protein. & Isoform B: Cell membrane; Single-pass type I membrane protein. & Isoform C: Cell membrane; Single-pass type I membrane protein. & Isoform G: Secreted. & Isoform H: Secreted. & Isoform I: Secreted.DISEASE:SwissProt: P13688 # Loss or reduced expression is a major event in colorectal carcinogenesis. & Increased serum levels of BGP-1 are found in individuals suffering from hepatic disorders.SIMILARITY: SwissProt: P13688 ## Belongs to the immunoglobulin superfamily. CEA family. & Contains 3 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 Ig-like V-type (immunoglobulin-like) domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Carcinoembryonic Antigen Antibody, clone 1105 | MAB425 View All» Concentration: 2.86 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 500 µg View All» Format: Purified View All» Host: Mouse View All»
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