货号：MAB396

品牌：Merck Millipore

规格：100Ug

目录价：￥4967.00

市场价格：￥4221.95

会员价格：￥3973.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11 | MAB396 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Glutamate Receptor 2 (GluR2) by Western blot and RIA. When using MAB396 for immunohistochemistry or immunoprecipitation it recognizes both GluR2 and GluR4. View All» Immunogen: Recombinant fusion protein TrpE-GluR2 View All» Clone: 3A11 View All» Isotype: IgG2a View All» Species Reactivity:

• Human

• Monkey

• Rat
  View All» Application Notes: Immunohistochemistry on 4% paraformaldehyde fixed tissue: 1:500-1,000 Immunocytochemistry ELISA RIA Optimal working dilutions must be determined by end user. View All» Presentation: Purified immunoglobulin. Liquid in PBS, no preservative. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up 12 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number:
  • Q14416

  • Q14833
    View All» Entrez Gene Number: NM_000839.2 View All» Gene Symbol:
    • GRM2

    • mGlu2

    • GPRC1B

    • MGLUR2

    • mGluR2

    • GLUR2
      View All» Alternate Names: GluR2/4 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • ELISA

      • Immunocytochemistry

      • Immunohistochemistry

      • Immunoprecipitation

      • Radioimmunoassay

      • Western Blotting
        View All» Entrez Gene Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. View All» UniProt Summary: FUNCTION: SwissProt: Q14833 # Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.SIZE: 912 amino acids; 101868 Da SUBUNIT: Interacts with PRKCABP (By similarity).SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver.SIMILARITY: SwissProt: Q14833 ## Belongs to the G-protein coupled receptor 3 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11 | MAB396 View All» Concentration: 1.7 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
        © 金山科研平台是专业的授权总代理区域代理经销平台。
        © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
        © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
        © 本文地址：https://16ao.com/thread-131454.htm
        © Merck Millipore代理MAB396 Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11;store at -20℃，产品报价联系微信jinshanbio