货号：MAB3864

品牌：Merck Millipore

规格：100Ug

目录价：￥6127.00

市场价格：￥5207.95

会员价格：￥4901.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-DNA/Histone H1 Antibody | MAB3864 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with DNA/Histone 1. The antibody can be used to stain nuclei of all species and to identify necrosis. By immunohistochemistry, the antibody shows dense staining of nuclei with no staining of nucleoli observed. View All» Immunogen: Human Raji cell nuclei View All» Isotype: IgG2a View All» Species Reactivity: All View All» Application Notes: Immunocytochemistry: 5-10 μg/mL on 2% paraformaldehyde fixed cells (10 minutes at room temperature) Immunohistochemistry: 5-10 μg/mL on paraformaldehyde or B5 fixed tissue sections. Flow cytometry: 5-10 μg/mL using 2% paraformaldehyde fixed cells. ELISA, direct and indirect Optimal working dilutions must be determined by end user. STAINING PATTERN: Nuclear staining observed. Dense staining of nuclei. No staining of nucleoli. View All» Presentation: Protein A purified culture supernatant. Liquid in PBS View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P10412 View All» Entrez Gene Number: NM_005321.2 View All» Gene Symbol:

• HIST1H1E

• H1.4

• dJ221C16.5

• H1F4

• MGC116819
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Flow Cytometry

  • Immunocytochemistry

  • Immunohistochemistry
    View All» Entrez Gene Summary: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. View All» UniProt Summary: FUNCTION: SwissProt: P10412 # Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.SIZE: 219 amino acids; 21865 Da SUBCELLULAR LOCATION: Nucleus.SIMILARITY: SwissProt: P10412 ## Belongs to the histone H1/H5 family. MISCELLANEOUS: This variant accounts for 60% of histone H1. View All» Brand Family: Chemicon View All» Product Name: Anti-DNA/Histone H1 Antibody | MAB3864 View All» Concentration: 1.4 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Mouse View All»
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