货号：MAB3808

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Mannan-Binding Lectin Antibody | MAB3808 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with Mannan (Mannose)-Binding Lectin (MBL). Recognizes both natural and recombinant protein. View All» Immunogen: Natural MBL from human plasma. View All» Isotype: IgG1 View All» Species Reactivity: Human View All» Application Notes: Western blot: 1:5,000-1:10,000. Reacts with the ~30 kDa human MBL protein. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 with 5% skim milk. Suggested incubation time is one hour at room temperature. ELISA (direct and indirect): 1:5,000-1:10,000 Optimal working dilutions must be determined by end user. View All» Presentation: Liquid ascites containing no preservative. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Important Note: During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap. View All» UniProt Number: P11226 View All» Entrez Gene Number: NM_000242.1 View All» Gene Symbol:

• MBL2

• MBP

• MGC116832

• HSMBPC

• MBL

• MGC116833

• MBP-C

• COLEC1

• MBP1
  View All» Alternate Names: MBL View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Western Blotting
    View All» Entrez Gene Summary: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. View All» UniProt Summary: FUNCTION: SwissProt: P11226 # Binds mannose and N-acetylglucosamine in a calcium- dependent manner. Is capable of host defense against pathogens, by activating the classical complement pathway independently of the antibody.SIZE: 248 amino acids; 26144 Da SUBUNIT: Oligomeric complex of 6 set of homotrimers. Binds MASP2.DISEASE: SwissProt: P11226 # There is an association between low levels of MBL2 and a defect of opsonization which results in susceptibility to frequent and chronic infections. & Genetic variations in MBL2 are associated with susceptibility to hepatitis B virus infection (HBV infection) [MIM:610424]. Approximately one third of all cases of cirrhosis and half of all cases of hepatocellular carcinoma can be attributed to chronic HBV infection. HBV infection may result in subclinical or asymptomatic infection, acute self-limited hepatitis, or fulminant hepatitis requiring liver transplantation.SIMILARITY: SwissProt: P11226 ## Contains 1 C-type lectin domain. & Contains 1 collagen-like domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Mannan-Binding Lectin Antibody | MAB3808 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
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