货号：MAB362

品牌：Merck Millipore

规格：100UL

目录价：￥6127.00

市场价格：￥5207.95

会员价格：￥4901.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MAP1 Antibody, clone HM-1 | MAB362 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts specifically with MAP1 (also known as MAP 1a) on immunoblots of whole brain homogenate proteins. Shows selective staining of neurons and stronger staining of axons and dendrites in immunohistochemistry staining of brain tissue. Stains both the cell bodies and dendritic trees. No cross-reactivity observed to other MAPs or tubulin. View All» Immunogen: Rat brain microtubule-associated protein. View All» Clone: HM-1 View All» Isotype: IgG1 View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Immunoblotting at 1:500 using fresh rat brain extract or enriched microtubule protein preparation. Immunocytochemistry Optimal working dilutions must be determined by end user. View All» Presentation: Ascites fluid. Liquid containing 15mM sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For antibodies with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap. View All» UniProt Number: P78559 View All» Entrez Gene Number: NM_002373.5 View All» Gene Symbol:
  • MAP1A

  • FLJ77111

  • MTAP1A

  • MAP1L
    View All» Alternate Names: Microtubule-Associated Protein View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunocytochemistry

    • Immunohistochemistry
      View All» Entrez Gene Summary: This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development. View All» UniProt Summary: FUNCTION: SwissProt: P78559 # Structural protein involved in the filamentous cross- bridging between microtubules and other skeletal elements.SIZE: 2805 amino acids; 306482 Da SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. Interacts with guanylate kinase- like domain of DLG1, DLG2 and DLG4 (By similarity).TISSUE SPECIFICITY: Brain.DOMAIN: SwissProt: P78559 The basic region containing the repeats may be responsible for the binding of MAP1A to microtubules.PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. & LC2 is generated from MAP1A by proteolytic processing.SIMILARITY: Belongs to the MAP1 family. View All» Brand Family: Chemicon View All» Product Name: Anti-MAP1 Antibody, clone HM-1 | MAB362 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
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