货号：MAB341

品牌：Merck Millipore

规格：100Ug

目录价：￥7049.00

市场价格：￥5991.65

会员价格：￥5639.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-GABA A Receptor β 2,3 Chain Antibody, clone BD17 | MAB341 View All» Replaces: AB5952 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with the β-chain of the GABAA receptor. View All» Molecular Weight: 55 kDa View All» Epitope: Extracellular domain of the beta2 & beta3 subunits of the GABAA receptor View All» Immunogen: Purified GABA/benzodiazepine receptor from bovine cortex View All» Clone: BD17 View All» Isotype: IgG1 View All» Background Information: Gamma-aminobutyric acid type A (GABAA) receptors are members of the neurotransmitter ligand-gated ion channels that mediate neuronal inhibition on binding GABA. The effects of GABA on GABAA receptors are modulated by a range of therapeutically important drugs, including barbiturates, anaesthetics and benzodiazepines. View All» Species Reactivity:

• Bovine

• Human

• Mouse

• Rat

• Monkey

• Feline
  View All» Species Reactivity Note: Expected to react with human and rat based on sequence homology. View All» Application Notes: Immunohistochemistry: A 10-20 μg/mL concetration of a previous lot was used in IH. Immunoprecipitation: A previous lot of this antibody was used in IP.Western blot: 5-20 µg/mL. Recognizes a 55 kDa band corresponding to the beta chain of the GABAA receptor.Optimal working dilutions must be determined by end user. View All» Control: HepG2 cell lysate View All» Quality Assurance: Evaluated by Western Blot on mouse brain membrane lysates.Western Blot: 1:500 dilution of this antibody detected GABA A Receptor β 2,3 Chain on 10 μg of mouse brain membrane lysates. View All» Purification Method: Protein A purfied View All» Presentation: Purified mouse monoclonal IgG1 liquid in buffer containing 10 mM potassium phosphate buffer pH 7.4 with 150 mM NaCl View All» Storage Conditions: Stable for 1 year at -20ºC from date of receipt. View All» UniProt Number: P47870 View All» Entrez Gene Number: NM_000813.2 View All» Gene Symbol:
  • GABRB2

  • GABA

  • MGC119388

  • MGC119389

  • MGC119386
    View All» Alternate Names:
    • GABA(A) receptor subunit beta-2

    • gamma-aminobutyric acid (GABA) A receptor, beta 2

    • gamma-aminobutyric acid A receptor, beta 2
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunohistochemistry

      • Immunoprecipitation

      • Western Blotting
        View All» Entrez Gene Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. View All» UniProt Summary: FUNCTION: SwissProt: P47870 # GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.SIZE: 474 amino acids; 54606 Da SUBUNIT: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Binds UBQLN1.SUBCELLULAR LOCATION: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.SIMILARITY: SwissProt: P47870 ## Belongs to the ligand-gated ionic channel (TC 1.A.9) family View All» Brand Family: Chemicon View All» Product Name: Anti-GABA A Receptor β 2,3 Chain Antibody, clone BD17 | MAB341 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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        © Merck Millipore代理MAB341 Anti-GABA A Receptor β 2,3 Chain Antibody, clone BD17;抗GABA A受体β2，3链抗体，克隆BD17store at -20℃，产品报价联系微信jinshanbio