Merck Millipore代理MAB3402X Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5, Alexa Fluor® 488;store at +2℃ to +8℃

2025-06-24

货号:MAB3402X

品牌:Merck Millipore

规格:100Ug

目录价:¥6434.00

市场价格:¥5468.90

会员价格:¥5147.20

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5, Alexa Fluor® 488 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: The antibody reacts with GFAP from human, pig, chicken and rat. In tissue sections this antibody stains astrocytes and Bergman glia cells (1). View All» Immunogen: Purified glial filament (1). View All» Isotype: IgG1 View All» Species Reactivity:

  • Chicken

  • Human

  • Pig

  • Rat

    View All» Application Notes: Immunocytochemistry Immunohistochemistry Optimal working dilutions must be determined by end user. View All» Presentation: Purified immunoglobulin conjugated to Alexa Fluor® 488. Liquid in Phosphate buffer with 15 mg/mL BSA as a stabilizer and 0.1% sodium azide. View All» Storage Conditions: Maintain at 2-8°C in the dark for up to 6 months after date of receipt. View All» UniProt Number: P14136 View All» Entrez Gene Number: NM_002055.2 View All» Gene Symbol:
    • GFAP

    • FLJ45472

      View All» Alternate Names: GFAP View All» Usage Statement:
      • Alexa Fluor® is a registered trademark of Molecular Probes, Inc.

      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

        View All» Key Applications:
        • Immunocytochemistry

        • Immunohistochemistry

          View All» Entrez Gene Summary: This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant has been described, but its full length sequence has not been determined. View All» UniProt Summary: FUNCTION: SwissProt: P14136 # GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.SIZE: 432 amino acids; 49880 Da SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1.SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments.DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander disease [MIM:203450]. Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. The most common form affects infants and young children, and is characterized by progressive failure of central myelination, usually leading to death usually within the first decade. Infants with Alexander disease develop a leukoencephalopathy with macrocephaly, seizures, and psychomotor retardation. Patients with juvenile or adult forms typically experience ataxia, bulbar signs and spasticity, and a more slowly progressive course.SIMILARITY: SwissProt: P14136 ## Belongs to the intermediate filament family. View All» Brand Family: Chemicon View All» Product Name: Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5, Alexa Fluor® 488 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: AlexaFluor®488 View All» Host: Mouse View All»

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