货号：MAB338

品牌：Merck Millipore

规格：100Ug

目录价：￥6127.00

市场价格：￥5207.95

会员价格：￥4901.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Ciliary Neurotrophic Factor Antibody, clone 4-68 | MAB338 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Ciliary neurotrophic factor. Detects a 22 kD band in Western blots of rat sciatic nerve extract. View All» Immunogen: Purified ciliary neurotrophic factor from rat sciatic nerve. View All» Clone: 4-68 View All» Isotype: IgG1 View All» Species Reactivity:

• Human

• Mouse

• Monkey

• Rat
  View All» Application Notes: Immunohistochemistry: 10-20 μg/mL on frozen sections of rat sciatic nerve perfused and counter-fixed with 4% paraformaldehyde (Stockli et al., 1991). Western blotting: 10 μg/mL (Stockli et al., 1991) Optimal working dilutions must be determined by the end user. View All» Presentation: Liquid in 0.02M phosphate buffer, 0.25M NaCl with 0.1% sodium azide, pH 7.6. View All» Storage Conditions: Maintain at 2-8°C for up to 6 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P26441 View All» Entrez Gene Number: NM_000614.2 View All» Gene Symbol:
  • CNTF

  • HCNTF
    View All» Alternate Names: CNTF View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry
      View All» Entrez Gene Summary: The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also co-transcribed with the upstream ZFP91 gene. Co-transcription from the two loci results in a transcript that contains a complete coding region for the zinc finger protein but lacks a complete coding region for ciliary neurotrophic factor. View All» UniProt Summary: FUNCTION: SwissProt: P26441 # CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.SIZE: 200 amino acids; 22931 Da SUBUNIT: Homodimer.SUBCELLULAR LOCATION: Cytoplasm.TISSUE SPECIFICITY: Nervous system.SIMILARITY: SwissProt: P26441 ## Belongs to the CNTF family. View All» Brand Family: Chemicon View All» Product Name: Anti-Ciliary Neurotrophic Factor Antibody, clone 4-68 | MAB338 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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