货号：03-185

品牌：Merck Millipore

规格：

目录价：￥3632.00

市场价格：￥3087.20

会员价格：￥2905.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Histone H2B human recombinant View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 50 µg View All» Product Overview: Human recombinant H2B expressed in E. Coli View All» Background Information: Histone H2B is one of four core histones that form an octameric structure required for the packaging of DNA into nucleosomes, the most basic level of chromatin arrangement. Histones undergo a number of post-translational modifications (PTM) at their N- and C-terminal tails which can influence chromatin structure and stability and consequently, transcription, and DNA replication and repair. The most widely studied of these modifications are methylation, phosphorylation, and acetylation which may produce different effects on gene regulation depending on the number and pattern of modifications. Histone H2B undergoes acetylation at lysines 5, 15, and 20. It is also phosphorylated in apoptotic cells during DNA fragmentation, possibly in a caspase-dependent manner. View All» Key Applications:

• Kinase Assay

• DNA-binding Proteins

• Western Blotting
  View All» Application Notes: Chromatin assembly, Western blot (control), Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Species: Human View All» Molecular Weight: ~17 kDa View All» Brand Family: Upstate View All» Presentation: Liquid in Dulbecco's PBS View All» Storage Conditions: Stable for 12 months at -80ºC from date of receipt. Avoid multiple freeze/thaw cycles. View All» Product Name: Histone H2B human recombinant View All» Physical Form: Frozen solution View All» Format: Purified View All» Host: E. coli View All» Purity: Purity >95% by SDS-PAGE View All»
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