货号：03-182

品牌：Merck Millipore

规格：1EA

目录价：￥6729.15

市场价格：￥5719.78

会员价格：￥5383.32

金山科研平台，产品价格货期咨询微信：jinshanbio Description: HDAC2 (1-488) (His-tag) human recombinant View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 50 µg View All» Product Overview: Human recombinant HDAC2 (1-488) (His-tag) produced in insect cells View All» Background Information: Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDAC2 is likely to be involved in regulating chromatin structure during transcription. It associates with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA. This process is highly conserved from yeast to human. View All» Key Applications: Enzyme Assay View All» Application Notes: HDAC deacetylase assays View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Species: Human View All» Molecular Weight: ~55 kDa View All» Brand Family: Upstate View All» Source: Residues 1-488 of human HDAC2 View All» Presentation: In liquid containing 50 mM Tris, pH 8.0, 138 mM NaCl and 10% glycerol View All» Storage Conditions: Store at -80°C. The enzyme is stable on ice for 30 to 60 min, but may lose activity with dilution and/or prolonged storage on ice. It is recommended that thawing and addition of the enzyme to assay wells be done within as short a time as possible before start of the assay and that the thawed enzyme be kept on ice throughout. Best performance will be obtained by adding the chilled, undiluted enzyme directly to pre-warmed buffer and proceeding immediately to the addition of pre-warmed substrate. The remaining, unused enzyme should be refrozen quickly by, for example, snap freezing in a dry/ice ethanol bath or liquid nitrogen. The enzyme is stable to at least 4 freeze/thaw cycles. To minimize the number of freeze/thaw cycles, aliquot the HDAC2 into separate tubes before storing at -80°C. View All» Product Name: HDAC2 (1-488) (His-tag) human recombinant View All» Physical Form: Frozen solution View All» Format: Purified View All» Specific Activity: >5 U/µg. 1U = 1 pmol/min at 37°C using a standard flourometric activity assay to measure deacetylation activity. View All» Purity: Purity >50% by SDS-PAGE View All»