货号：MAB3310

品牌：Merck Millipore

规格：1EA

目录价：￥5125.68

市场价格：￥4356.83

会员价格：￥4100.54

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-TIMP-2 Antibody, clone 67-4H11 | MAB3310 View All» Replaces: MAB3356 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: The antibody specifically reacts with human TIMP-2. SPECIES REACTIVITY: Cross-reacts with mouse, rat, guinea pig, rabbit and bovine TIMP-2. View All» Immunogen: Synthetic peptide corresponding to amino acids 178-193 of human TIMP-2 (numbered from the propeptide) YRGAAPPKQEFLDIED View All» Clone: 67-4H11 View All» Isotype: IgG1κ View All» Species Reactivity:

• Bovine

• Guinea Pig

• Goat

• Human

• Mouse

• Rat

• Rabbit
  View All» Application Notes: Immunoblotting Immunohistochemistry on paraffin-embedded, PLP fixed tissue at 5 μg/mL (see Tomita reference) or frozen tissues at 1 μg/mL (see Ohashi reference). ElA View All» Presentation: Liquid in 0.1M Na-Phosphate buffer, pH 7.0 containing 2% protease free bovine serum albumin. View All» Storage Conditions: Maintain frozen at -20°C in undiluted aliquots for up to 12 months. View All» UniProt Number: P16035 View All» Entrez Gene Number: NM_003255.4 View All» Gene Symbol:
  • TIMP2

  • TIMP-2

  • CSC-21K
    View All» Alternate Names: Tissue Inhibitor of Metalloproteinase-2 View All» Sales Restrictions: This product is not available for sale in Japan. View All» Usage Statement:
    • Manufactured by Daiichi Fine Chemical Co., Ltd

    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      View All» Key Applications:
      • ELISA

      • Western Blotting

      • Immunohistochemistry (Paraffin)
        View All» Entrez Gene Summary: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. View All» UniProt Summary: FUNCTION: SwissProt: P16035 # Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.SIZE: 220 amino acids; 24399 Da SUBCELLULAR LOCATION: Secreted.PTM: The activity of TIMP2 is dependent on the presence of disulfide bonds.SIMILARITY: SwissProt: P16035 ## Belongs to the protease inhibitor I35 (TIMP) family. & Contains 1 NTR domain. View All» Brand Family: Chemicon View All» Product Name: Anti-TIMP-2 Antibody, clone 67-4H11 | MAB3310 View All» Concentration: 2 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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