货号：MAB3272

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Surfactant Protein A Antibody, clone 3-4 | MAB3272 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with canine SP-A. View All» Immunogen: Canine SP-A purified from lavage material. View All» Clone: 3-4 View All» Isotype: Ig View All» Species Reactivity: Canine View All» Application Notes: ELISA Optimal dilutions must be determined by the end user. View All» Presentation: Liquid. Contains no preservative View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to twelve months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q8IWL2 View All» Entrez Gene Number: NM_001093770.1 View All» Gene Symbol:

• SFTPA1

• SFTP1

• COLEC4

• PSPA

• SFTPA

• PSP-A

• PSAP

• SP-A1

• SP-A
  View All» Alternate Names: SP-A View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: ELISA View All» UniProt Summary: FUNCTION: SwissProt: Q8IWL2 # In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.SIZE: 248 amino acids; 26242 Da SUBUNIT: Oligomeric complex of 6 set of homotrimers.SUBCELLULAR LOCATION: Secreted, extracellular space.DISEASE: SwissProt: Q8IWL2 # Genetic variations in SFTPA1 are associated with respiratory distress syndrome in premature infants (RDS) [MIM:267450]; also known as RDS in prematurity. RDS in the newborn is the main cause of mortality and morbidity in premature infants. RDS is characterized by deficient gas exchange that is caused by diffuse atelectasis and high-permeability lung edema that results in fibrin-rich alveolar deposits called 'hyaline membranes'. The risk of bronchopulmonary dysplasia increases with the severity of RDS.SIMILARITY: SwissProt: Q8IWL2 ## Contains 1 C-type lectin domain. & Contains 1 collagen-like domain. MISCELLANEOUS: Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C). View All» Brand Family: Chemicon View All» Product Name: Anti-Surfactant Protein A Antibody, clone 3-4 | MAB3272 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Target / Localization: Pulmonary airways, Eustachian tube epithelia, Type II alveolar cells and Clara cells View All» Format: Ascites View All» Host: Mouse View All»
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