货号：MAB1933

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Fibronectin, pepsin cell binding site, clone 790D24 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes a pepsin cleavage site at the amino terminus of the 11kd cell adhesive sequence and it inhibits cell binding to fibronectin. . View All» Epitope: pepsin cell binding site View All» Immunogen: Human plasma fibronectin. View All» Clone: 790D24 View All» Isotype: IgG1 View All» Species Reactivity: Human View All» Application Notes: ELISA Microscopy Western blotting at 1-5 μg/ml Cellular Adhesion Studies Final working dilutions must be determined by end user. View All» Presentation: Liquid in 0.02M PBS, 0.25M NaCl, pH 7.4, 0.1% sodium azide View All» Storage Conditions: Maintain at 2-8°C . View All» UniProt Number: P02751 View All» Entrez Gene Number:

• NM_002026.2

• NM_054034.2

• NM_212474.1

• NM_212475.1

• NM_212476.1

• NM_212478.1

• NM_212482.1
  View All» Gene Symbol:
  • FN1

  • DKFZp686H0342

  • DKFZp686I1370

  • MSF

  • CIG

  • LETS

  • DKFZp686O13149

  • FN

  • DKFZp686F10164

  • FINC
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. View All» UniProt Summary: FUNCTION: SwissProt: P02751 # Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Interaction with TNR mediates inhibition of cell adhesion and neurite outgrowth (By similarity).SIZE: 2386 amino acids; 262607 Da SUBUNIT: Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1, AMBP, TNR, LGALS3BP and COL13A1.SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.TISSUE SPECIFICITY: Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.DEVELOPMENTAL STAGE: Ugl-Y1, Ugl-Y2 and Ugl-Y3 are present in the urine from 0 to 17 years of age.PTM: Sulfated.SIMILARITY: SwissProt: P02751 ## Contains 12 fibronectin type-I domains. & Contains 2 fibronectin type-II domains. & Contains 16 fibronectin type-III domains. View All» Brand Family: Chemicon View All» Product Name: Anti-Fibronectin, pepsin cell binding site, clone 790D24 View All» Concentration: 1mg/ml View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 500 µg View All» Format: Purified View All» Host: Mouse View All»
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