货号：MAB19104

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Integrin α2β1, clone BMA2.M View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Directed against mouse integrin alpha2beta1 heterodimer. Antibody does not recognize the alpha2 or beta1 subunits individually. View All» Immunogen: Mouse integrin alpha2beta1 heterodimer View All» Clone: BMA2.M View All» Isotype: IgM View All» Species Reactivity: Mouse View All» Application Notes: Flow cytometry Not effective for immunohistochemistry Optimal working dilutions must be determined by end user. View All» Applications Not Recommended: Immunohistochemistry View All» Presentation: Unpurified tissue culture supernatant from a perfusion system, filtered through a 0.2μ micron membrane prior to vialing. Product contains 20%FBS and Ciprofloxacin at final concentration of 10μg/mL. View All» Storage Conditions: Maintain at 2-8°C for up to 12 months. View All» UniProt Number: P17301 View All» Entrez Gene Number: NM_002203.3 View All» Gene Symbol:

• ITGA2

• CD49B

• VLAA2

• VLA-2

• CD49b

• BR

• GPIa
  View All» Alternate Names: VLA-2 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Flow Cytometry View All» Entrez Gene Summary: This gene product belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including, T cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling. View All» UniProt Summary: FUNCTION: SwissProt: P17301 # Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.SIZE: 1181 amino acids; 129295 Da SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-2 associates with beta-1. Interacts with HPS5.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.DOMAIN: SwissProt: P17301 The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.SIMILARITY: Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats. & Contains 1 VWFA domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Integrin α2β1, clone BMA2.M View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 500 µL View All» Format: Culture Supernatant View All» Host: Rat View All»
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