货号：MAB1800

品牌：Merck Millipore

规格：

目录价：￥5571.00

市场价格：￥4735.35

会员价格：￥4456.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Cytochrome C Antibody, clone 7H8.2C12 | MAB1800 View All» Replaces: MAB3916 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: MAB1800 reacts with denatured human, mouse and rat Cytochrome C. The antibody does not bind native Cytochrome C. View All» Immunogen: Pigeon Cytochrome C View All» Clone: 7H8.2C12 View All» Isotype: IgG2b View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Application Notes: Western blot: 1:400 The antibody detects a 12 kDa protein corresponding to the apparent molecular weight of Cytochrome C. Optimal working dilutions must be determined by end user. View All» Presentation: Affinity purified immunoglobulin. Liquid in PBS containing 0.5% BSA, 0.01% Thimerosal and 50% glycerol. View All» Storage Conditions: Maintain frozen at -20°C. For storage up to 12 months, aliquot and refreeze at -20°C or -70°C. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P99999 View All» Entrez Gene Number: NM_018947.4 View All» Gene Symbol:
  • CYCS

  • CYC

  • HCS
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene encodes cytochrome c, a component of the electron transport chain in mitochondria. The heme group of cytochrome c accepts electrons from the b-c1 complex and transfers electrons to the cytochrome oxidase complex. Cytochrome c is also involved in initiation of apoptosis. Upon release of cytochrome c to the cytoplasm, the protein binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Many cytochrome c pseudogenes exist, scattered throughout the human genome. View All» UniProt Summary: FUNCTION: SwissProt: P99999 # Plays a role in apoptosis. Suppression of the anti- apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.SIZE: 105 amino acids; 11749 Da SUBCELLULAR LOCATION: Mitochondrion matrix.PTM: Binds 1 heme group per subunit.SIMILARITY: SwissProt: P99999 ## Belongs to the cytochrome c family. View All» Brand Family: Chemicon View All» Product Name: Anti-Cytochrome C Antibody, clone 7H8.2C12 | MAB1800 View All» Concentration: 0.2 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Mouse View All»
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