货号：9083

品牌：Merck Millipore

规格：EA

目录价：￥2106.00

市场价格：￥1790.10

会员价格：￥1684.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Rat Leptin View All» Qty/Pk: 250 tubes View All» Background Information: These iodinated hormonos are HPLC purified and prepared fresh monthly. View All» Application Notes: appropriate label hydrating buffer if kit replacement or assay buffer of choice View All» Entrez Gene Summary: This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. View All» UniProt Summary: FUNCTION: SwissProt: P41159 # May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.SIZE: 167 amino acids; 18641 Da SUBUNIT: Interacts with SIGLEC6.SUBCELLULAR LOCATION: Secreted.DISEASE:SwissProt: P41159 # Defects in LEP may be a cause of autosomal recessive obesity [MIM:601665].SIMILARITY: SwissProt: P41159 ## Belongs to the leptin family. View All» Species: Rat View All» Label: ¹²⁵Iodine View All» UniProt Number:

• P50596

• P41159
  View All» Radioactivity: View All» Storage Conditions: 2–8°C View All» Product Name: Rat Leptin View All»
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