货号：9016

品牌：Merck Millipore

规格：

目录价：￥2741.00

市场价格：￥2329.85

会员价格：￥2192.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Lis/Pro Insulin View All» Qty/Pk: 250 tubes View All» Background Information: These iodinated hormonos are HPLC purified and prepared fresh monthly. View All» Application Notes: appropriate label hydrating buffer if kit replacement or assay buffer of choice View All» Entrez Gene Summary: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. View All» UniProt Summary: FUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.SIZE: 110 amino acids; 11981 Da SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.SUBCELLULAR LOCATION: Secreted.DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family. View All» Label: ¹²⁵Iodine View All» UniProt Number: P01308 View All» Radioactivity: View All» Storage Conditions: 2–8°C View All» Gene Symbol:

• INS

• proinsulin

• insulin
  View All» Product Name: Lis/Pro Insulin View All» Entrez Gene Number: NM_000207.2 View All»
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