货号：MAB1590

品牌：Merck Millipore

规格：EA

目录价：￥4270.00

市场价格：￥3629.50

会员价格：￥3416.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Na+/Ca++ Exchanger Antibody, clone 6H2 | MAB1590 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Strong and specific immunolabeling of 160 and 120 kD Na+/Ca++ Exchanger (NCX1) proteins in Western blot. In some preparations a 70kDa band breakdown fragment can also be observed. Membrane preparations are recommend that contain proteinase inhibitors. View All» Immunogen: Fusion protein from rabbit renal Na+/Ca++ Exchanger. View All» Clone: 6H2 View All» Isotype: IgG2b View All» Species Reactivity:

• Mouse

• Monkey

• Rat

• Rabbit
  View All» Application Notes: Western blot: 1:100-1:1000 (35S-protein A); Higher working dilutions may be necessary using ECL. Immunohisto/cytochemistry: 1:200-1:1000 Immunoprecipitation ELISA Optimal working dilutions must be determined by end user. View All» Presentation: Purified immunoglobulin from culture supernatant. Lyophilized from 5 mM ammonium biocarbonate. Contains no preservative. Reconstitute with 50 μL of PBS. View All» Storage Conditions: Maintain lyophilized material at -20°C for up to six months after receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P32418 View All» Entrez Gene Number: NM_021097.2 View All» Gene Symbol:
  • SLC8A1

  • CNC

  • NCX1

  • Na

  • DKFZp779F0871

  • +Ca

  • MGC119581
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Immunocytochemistry

    • Immunohistochemistry

    • Immunoprecipitation

    • Western Blotting
      View All» Entrez Gene Summary: In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: P32418 # Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.SIZE: 973 amino acids; 108547 Da SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.TISSUE SPECIFICITY: Cardiac sarcolemma.SIMILARITY: SwissProt: P32418 ## Belongs to the sodium/potassium/calcium exchanger family. SLC8 subfamily. & Contains 2 Calx-beta domains. View All» Brand Family: Chemicon View All» Product Name: Anti-Na+/Ca++ Exchanger Antibody, clone 6H2 | MAB1590 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://16ao.com/thread-130064.htm
      © Merck Millipore代理MAB1590 NA/CA EXCHANGER, MS X-100UG，产品报价联系微信jinshanbio