货号：MAB1567A4

品牌：Merck Millipore

规格：1EA

目录价：￥5820.63

市场价格：￥4947.54

会员价格：￥4656.50

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-MAG Antibody, clone 513, Alexa Fluor® 488 Conjugate | MAB1567A4 View All» Promotional Text: Special Offer on Antibodies! Click Here! View All» Molecular Weight: 69 kDa calculated View All» Immunogen: L2 epitope carrying glycoprotein extract of 1-2 day old chicken brain View All» Clone: 513 View All» Isotype: IgG1 View All» Background Information: Myelin-associated glycoprotein (MAG), a member of the immunoglobulin superfamily, is a membrane glycoprotein of 100 kDa, and is thought to be involved in the process of myelination. Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin, Nogo and MAG. MAG has been implicated in the inhibition of nerve regeneration in the CNS. View All» Species Reactivity:

• Rat

• Mouse

• Human

• Bovine

• Chicken

• Frog
  View All» Species Reactivity Note: Demonstrated to react with Rat and Mouse. Predicted to react with Human, Bovine, Chicken, and Frog based on 100% sequence homology. View All» Application Notes: Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected MAG in rat E18 primary cortex cells. View All» Control: Adult mouse brain tissue View All» Quality Assurance: Evaluated by Immunohistochemistry in adult mouse brain tissue.Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected MAG in adult mouse brain tissue. View All» Purification Method: Protein A purified View All» Presentation: Purified mouse monoclonal IgG1 conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA. View All» Storage Conditions: Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt. View All» UniProt Number: P20916 View All» Entrez Gene Number: NP_002352 View All» Gene Symbol:
  • MAG

  • GMA
    View All» Alternate Names:
    • Myelin-associated glycoprotein

    • Siglec-4a
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunocytochemistry

      • Immunohistochemistry
        View All» Entrez Gene Summary: The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. View All» UniProt Summary: FUNCTION: Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha2,3- linked sialic acid (By similarity).SIZE: 626 amino acids; 69069 Da SUBUNIT: Binds to RTN4R (By similarity).SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.SIMILARITY: Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. & Contains 4 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 Ig-like V-type (immunoglobulin-like) domain. View All» Product Name: Anti-MAG, clone 513, Alexa Fluor® 488 Conjugate View All» Qty/Pk: 100 µL View All» Format: AlexaFluor®488 View All» Host: Mouse View All»
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