货号:MAB1398Z
品牌:Merck Millipore
规格:100Ug
目录价:¥5666.00
市场价格:¥4816.10
会员价格:¥4532.80
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Description:
Anti-PECAM-1 Antibody, clone 2H8, Azide Free | MAB1398Z
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Trade Name:
Chemicon (Millipore)
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Specificity:
React s with the 130-140 kDa protein, PECAM-1 found on mouse monocytes, platelets, granulocytes and endothelial cells. 2H8 effectively inhibits transmigration of activated polymophonuclear cells and monocytes across the endothelium. In a mouse model for acute peritonis - 2H8 blocks acute inflammation.
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Clone:
2H8
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Isotype:
IgG
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Background Information:
CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and platelets.CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).
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Species Reactivity:
Mouse
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Application Notes:
Flow Cytometry: 0.1 μg/mL Blocking Optimal working dilutions must be determined by end user.
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Control:
Mouse cell lung tissue
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Purification Method:
Protein A purfied
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Presentation:
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, containing no preservatives.
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Storage Conditions:
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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UniProt Number:
P69905
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Gene Symbol:
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ENSG00000188536
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HBA2
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Alpha-globin
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Alternate Names:
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CD31
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MAB1398
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
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Flow Cytometry
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Affects Function
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Brand Family:
Chemicon
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Product Name:
Anti-PECAM-1 Antibody, clone 2H8, Azide Free | MAB1398Z
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Concentration:
1.07 mg/mL
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Antibody Type:
Monoclonal Antibody
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Qty/Pk:
100 μg
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Format:
Purified
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Host:
Armenian Hamster
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