Merck Millipore代理MAB1287 Anti-Nuclear Ribonucleoprotein Antibody, clone 58-15;store at -20℃

2025-06-28

货号:MAB1287

品牌:Merck Millipore

规格:100UL

目录价:¥5207.00

市场价格:¥4425.95

会员价格:¥4165.60

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Nuclear Ribonucleoprotein Antibody, clone 58-15 | MAB1287 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Stains nuclear ribonucleoprotein particles (RNP) in human cells. Does not cross react with mouse RNP, other species not tested. RNP are 20-80nm dense nuclear particles. Highest labeling densities are found in RNP, but heterochromatin, euchromatin and nucleoli are also stained. View All» Molecular Weight: 28 kDa View All» Clone: 58-15 View All» Isotype: IgM View All» Background Information: snRNPs or small nuclear ribonucleoproteins, are particles that combine with pre-mRNA and various proteins to form spliceosomes (a type of large molecular complex). SnRNPs "recognize" the places along a strand of pre-mRNA and are essential in the removal of introns. These molecules are found within the cell's nucleus. The two essential components of snRNPs are protein molecules and RNA. The RNA found within each snRNP particle is known as small nuclear RNA, or snRNA. These molecules are usually about 150 nucleotides long. The snRNA is bound by a Ribonuclear protein (RNP) to activate its enzymatic activity. The precise beginnings and ends of introns on the primary transcripts are marked by signals so that they can be recognized and removed. The intron-boundary signals are recognized by a short bit of RNA found in curious RNA-protein complexes known as the small nuclear ribonucleoprotein particles - snRNPs, for short. At least four different kinds of snRNPs cooperate in most splicing. The RNA in these particles is like ribosomal RNA in that it is used directly, and has both an enzymatic and a structural role. View All» Species Reactivity:

  • Human

  • Rat

    View All» Non-Reactive Species: Mouse View All» Application Notes: Indirect immunofluorescence: 1:20-1:30. Use 30-100 μl per well/slide. Immunohistochemistry in formalin fixed paraffin embedded tissues: requires citrate acid microwave or HIER pretreatment: 1:20-1:30 primary antibody dilution. Archival tissues will require more antibody than 24-48 fixed specimens. Optimal working dilutions must be determined by the end user. View All» Control: Jurkat whole cell lysate, K-562 whole cell lysate View All» Presentation: Hybridoma supernatant, concentrated by ammonium sulfate. Buffer: PBS with 0.1% sodium azide. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. View All» Alternate Names: RNP View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunofluorescence

    • Immunohistochemistry

    • Immunohistochemistry (Paraffin)

      View All» Brand Family: Chemicon View All» Product Name: Anti-Nuclear Ribonucleoprotein Antibody, clone 58-15 | MAB1287 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Purified View All» Host: Mouse View All»

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