货号：MAB1086

品牌：Merck Millipore

规格：

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Eosinophil Major Basic Protein Antibody, clone AHE-2 | MAB1086 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts specifically from human eosinophil major basic protein from eosinophils among peripheral blood cells. Eosinophil major basic protein is felt to play an important role in eosinophil function and perhaps endothelial injury in hypereosinophilic states. View All» Clone: AHE-2 View All» Isotype: IgG1 View All» Species Reactivity: Human View All» Application Notes: ELISA at 1:800. Indirect immunofluorescence at 1:100-1:200. Optimal working dilutions must be determined by end user. View All» Presentation: Ascites fluid. Liquid. View All» Storage Conditions: Maintain at -20°C or colder in convenient aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P13727 View All» Entrez Gene Number: NM_002728.4 View All» Gene Symbol:

• PRG2

• MGC14537

• BMPG

• MBP
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • ELISA

  • Immunohistochemistry
    View All» Entrez Gene Summary: The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. View All» UniProt Summary: FUNCTION: SwissProt: P13727 # Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.SIZE: 222 amino acids; 25232 Da SUBUNIT: In pregnancy serum, the proform exists as a disulfide- linked 2:2 heterotetramer with PAPPA, as a disulfide-linked 2:2 heterotetramer with AGT, and as a complex (probably a 2:2:2 heterohexamer) with AGT and C3dg.SUBCELLULAR LOCATION: Note=The proform is secreted. The mature protein is found in the matrix of the eosinophil's large specific granule (crystalloid core).TISSUE SPECIFICITY: High levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon.DEVELOPMENTAL STAGE: Levels of the proform increase in serum and placenta during pregnancy.SIMILARITY: SwissProt: P13727 ## Contains 1 C-type lectin domain.MISCELLANEOUS: Binds heparin. Does not bind calcium. View All» Brand Family: Chemicon View All» Product Name: Anti-Eosinophil Major Basic Protein Antibody, clone AHE-2 | MAB1086 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://16ao.com/thread-129693.htm
    © Merck Millipore代理MAB1086 EOSIN MAJ BAS PROT, MS X-100UL；该产品已停产，产品报价联系微信jinshanbio