货号：MAB10422

品牌：Merck Millipore

规格：100Ug

目录价：￥5513.00

市场价格：￥4686.05

会员价格：￥4410.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Plexin-A3 Antibody, clone 18A9.2 | MAB10422 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~220 kDa observed. The calculated molecular weight of this protein is 208 kDa; however, a higher band may be observed due to glycosolation. View All» Immunogen: GST-tagged recombinant protein corresponding to human Plexin-A3. View All» Clone: 18A9.2 View All» Isotype: IgG1κ View All» Background Information: Plexin-A3 is a cell surface receptor for semaphorin that controls signaling for neuronal axon regulation. Plexin-A3 is thought to play a role in Sema3F and Sema3A signaling, has been described as essential for dorsal turning of the corticospinal tract axons and may be an important contributor to development of hippocampal axonal projections. Plexin-A3 has been found expressed in newly-differentiated sympathetic neurons, but not their neural crest precursors, and together with Plexin-A4, functions cooperatively to regulate the migration of sympathetic neurons and then differentially to guide the sympathetic axons. View All» Species Reactivity:

• Rat

• Human

• Mouse
  View All» Species Reactivity Note: Demonstrated to react with human, mouse, and rat. View All» Application Notes: Western Blot Analysis: 1 µg/mL from a previous lot detected Plexin-A3 on 10 µg of HT-29 and NIH/3T3 cell lysates.Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Plexin-A3 in colorectal carcinoma tissue. View All» Control: PC-12 cell lysate View All» Quality Assurance: Evaluated by Western Blot in PC-12 cell lysate.Western Blot Analysis: 1 µg/mL of this antibody detected Plexin-A3 on 10 µg of PC-12 cell lysate. View All» Purification Method: Protein G View All» Presentation: Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: P51805 View All» Entrez Gene Number: NP_059984 View All» Gene Symbol:
  • HSSEXGENE

  • SEX

  • XAP-6

  • PLXN3

  • PLXN4

  • Plxn3

  • PLXNA3
    View All» Alternate Names:
    • plexin A3

    • PLEXIN-A3

    • plexin-A3

    • Sex chromosome X transmembrane protein of HGF receptor family 3

    • Semaphorin receptor SEX

    • plexin-4

    • Plexin-4
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Entrez Gene Summary: The protein encoded by this gene is a member of the plexin class of proteins. The encoded protein is a transmembrane protein that is exposed on the cell surface. This gene is thought to be involved in epithelial and neural tissue development. [provided by RefSeq]. View All» UniProt Summary: FUNCTION: Putative receptor involved in the development of neural and epithelial tissues.SUBCELLUALR LOCATION: Membrane; Single-pass type I membrane protein (Potential). TISSUE SPECIFICTY: Predominant in neural tissue during development (By similarity); widely expressed in adult tissue.SEQUENCE SIMILARITIES: Belongs to the plexin family.Contains 4 IPT/TIG domains.Contains 1 Sema domain. View All» Product Name: Anti-Plexin-A3, clone 18A9.2 View All» Concentration: 1 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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