货号：MAB1040

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Calcium Calmodulin Antibody, clone ACC-1 | MAB1040 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes calcium-activated calmodulin and calcium-activated calmodulin phosphodiesterase complex. The epitope recognized by the antibody is absolutely calcium dependent; the antibody does not recognize calcium- free calmodulin or phosphodiesterase alone (Hansen, 1982). This antibody will recognize both the 61 and 63 kDa isoforms (CaM-PDE 1A and 1B, respectively) of active calmodulin-dependent phosphodiesterase in bovine and rat brain (Hansen, 1988). View All» Immunogen: Bovine brain calmodulin (CAM) complexed with bovine heart phosphodiesterase (PDE), calcineirin (CN), and myosin light chain kinase (MLCK). View All» Clone: ACC-1 View All» Isotype: IgG2b View All» Species Reactivity:

• Bovine

• Human

• Rat
  View All» Application Notes: Immunoprecipitation EIA Immunohistochemistry: 1:200 on paraffin-embedded or frozen tissue sections. NOTE: all proceedures must be performed in calcium-containing buffers without chelating agents (EGTA or EDTA). Optimal working dilutions must be determined by end user. View All» Presentation: Ascites fluid containing no preservatives. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P62158 View All» Entrez Gene Number: NM_006888.3 View All» Gene Symbol:
  • CALM1

  • CALML2

  • PHKD

  • CAMI

  • Calmodulin

  • CALM3

  • CALM

  • CaM

  • CALM2

  • CAM2

  • CAMB

  • CAMC

  • CAM3

  • DD132

  • CAM

  • CAM1

  • CAMIII
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Immunohistochemistry (Paraffin)

    • Immunoprecipitation
      View All» Entrez Gene Summary: Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found. They are identified by their occurrence in the cytosol or on membranes facing the cytosol and by a high affinity for calcium. Calmodulin contains 149 amino acids and has 4 calcium-binding domains. Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters.[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: P62158 # Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.SIZE: 149 amino acids; 16838 Da SUBUNIT: Interacts with TTN/titin and SRY.PTM: Ubiquitination results in a strongly decreased activity (By similarity). & Phosphorylation results in a decreased activity (By similarity).SIMILARITY: SwissProt: P62158 ## Belongs to the calmodulin family. & Contains 4 EF-hand domains.MISCELLANEOUS: This protein has four functional calcium-binding sites. View All» Brand Family: Chemicon View All» Product Name: Anti-Calcium Calmodulin Antibody, clone ACC-1 | MAB1040 View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Ascites View All» Host: Mouse View All»
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