货号：MAB10109

品牌：Merck Millipore

规格：EA

目录价：￥3828.00

市场价格：￥3253.80

会员价格：￥3062.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Apoptotic Neutrophils Antibody, clone BOB78 | MAB10109 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Antibody recognizes BOB78. View All» Molecular Weight: 90 kDa View All» Epitope: Unknown View All» Immunogen: Human whole apoptotic neutrophils BOB78 View All» Clone: BOB78 View All» Isotype: IgMκ View All» Background Information: Neutrophils are recruited in large numbers to inflammation sites. Clearance of these cells from the inflammatory site is done by programmed cell death (apoptosis) of the neutrophil. As a consequence, many cellular mechanisms are down-regulated in the apoptotic neutrophil such as: adhesion, chemotaxis, phagocytosis, enzyme secretion, generation of a respiratory burst, and responsiveness to external stimuli. Changes in the cell surface of dying neutrophils are recognized by macrophages, which destroy the neutrophils by phagocytosis. Many changes in the amount of proteins, carbohydrates and lipids on the surface of neutrophils are associated with the apoptotic event. Apoptotic Neutrophils (BOB78) is an up-regulated protein, molecular weight 90 kDa, that appears in the granular compartment of the late apoptotic neutrophil. This antigen does not appear in freshly isolated erythrocytes, platelets, lymphocytes, monocytes, or neutrophils. Monoclonal antibodies specific for BOB78 are a useful tool for studying the biology of apoptotic neutrophils. View All» Species Reactivity: Human View All» Species Reactivity Note: Demonstrated to react with human. View All» Control: THP-1 cells View All» Quality Assurance: Evaluated by Flow Cytometry in THP-1 cells.Flow Cytometry Analysis: 2 µg/mL of this antibody detected apoptotic neutrophils in THP-1 cells. View All» Purification Method: Ammonium sulfate precipitation View All» Presentation: Purified mouse monoclonal IgMκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide . View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:

• Flow Cytometry

• Immunoprecipitation

• Immunocytochemistry

• Immunohistochemistry
  View All» Product Name: Anti-Apoptotic Neutrophils, clone BOB78 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Purified View All» Host: Mouse View All»
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