货号：347200

品牌：BD IS

规格：100T

目录价：￥8217.00

市场价格：￥5751.90

会员价格：￥5341.05

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Catalog Number

347200

Name

CD326

Alias

EpCAM

Size

100Tests

RegulatoryStatus

RUO (GMP)

Clone

EBA-1

Format

APC

Isotype

IgG₁, λ

W.S. No

none

W.B. Positive Control

none

Molecular Weight

none

Reactivity

QC Testing : Human

Applications

Flow cytometry

- Routinely Tested

Clone - Description

Anti-EpCAM is directed against a human epithelial adhesion molecule (EpCAM) that has been identified as a 40-kilodalton (kd) protein in Western Blotting. This antigen is also known as epithelial surface antigen (ESA) and epithelial glycoprotein 2 (EGP-2).The epithelial cells present in non-squamous epithelia and tumors derived from such cells show EpCAM expression. The normal epithelial cells reactive with anti-EpCAM antibodies are those present in the (lower) respiratory tract; the (lower) gastrointestinal tract; tubules in the kidney; the surface epithelium of the ovary; the exocrine and endocrine pancreas; secondary germ cells of telogenic hair follicles; and secretory tubules of sweat glands in the skin, whereas the epidermis is negative. In addition, all epithelial cells in the thyroid and epithelial cells in the thymus show EpCAM expression, while the outer cortex and Hassall’s corpuscles have low expression. In the liver, only the bile ducts appear to be positive with anti-EpCAM antibodies. Non-squamous–carcinoma cells have high EpCAM expression, whereas such expression can also occur in squamous carcinoma. Tumors arising from non-epithelial cells, such as lymphoma, mesothelioma, neuroblastoma, and melanoma, do not express EpCAM.