货号：341007

品牌：BD IS

规格：50T

目录价：￥1427.00

市场价格：￥998.90

会员价格：￥927.55

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Catalog Number

341007

Name

CD23

Size

50Tests

RegulatoryStatus

RUO (GMP)

Clone

EBVCS-5

Format

PE

Isotype

IgG₁, κ

W.S. No

none

W.B. Positive Control

none

Molecular Weight

none

Reactivity

QC Testing : Human

Applications

Flow cytometry

- Routinely Tested

Clone - Description

CD23 recognizes a human B-lymphocyte differentiation antigen, Mr 45 kDa, that is the low-affinity Fc epsilon receptorThe CD23 antigen is present at low density on most normal B lymphocytes and at higher levels on activated B lymphocytes, Epstein-Barr virus (EBV)-transformed lymphoblasts, chronic lymphocytic leukemia (CLL) cells of B-lymphocyte origin, and tonsillar B lymphocytes. Human B-lymphoblastoid cell line RPMI-8866 releases a 25-kDa species into culture supernatant.CD23 antigen density increases on the surface of B lymphocytes shortly after activation. Expression is induced by interleukin-4 (IL-4) and down-regulated by B-cell growth factor (BCGF). The antigen is lost after isotype switching to IgA, IgG, or IgE. The CD23 antigen is not present on immature bone marrow B lymphocytes or on T lymphocytes, but it has been reported on monocytes, hypodense eosinophils, and a subpopulation of platelets.