货号：340420

品牌：BD IS

规格：50T

目录价：￥5707.00

市场价格：￥3994.90

会员价格：￥3709.55

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Catalog Number

340420

Name

CD134

Alias

OX40

Size

50Tests

RegulatoryStatus

RUO (GMP)

Clone

L106

Format

PE

Isotype

IgG₁, κ

W.S. No

none

W.B. Positive Control

none

Molecular Weight

none

Reactivity

QC Testing : Human

Applications

Flow cytometry

- Routinely Tested

Clone - Description

CD134 (Anti-Human Ox 40) recognizes a 50-kDa antigen that is present on activated T lymphocytes. By sequence analysis, it is related to the rat monoclonal antibody Ox 40, a member of the nerve growth factor superfamily that also includes CD27, CD30, CD40, CD95 (Fas), and the tumor necrosis factors alpha and beta (CD120a and CD120b).CD134 antigen (Human Ox 40) is found on activated peripheral CD4⁺ T lymphocytes and a subset of activated CD8⁺ T lymphocytes. It is not expressed on CD3-activated purified CD8⁺ T lymphocytes. It is also present on HUT-102, an HTLV-1–infected T-lymphocyte line. Its ligand, gp34, is found on Epstein-Barr virus (EBV)–transformed B lymphocytes. Preliminary evidence suggests a possible role for CD134 antigen in graft rejection.