eBioscience (含Bender)代理12-5760-82 Anti-Mouse Bcl-6 PE (To be Discontinued; See alternate clone, Cat. No. 12-5453)

2025-06-25

货号:12-5760-82

品牌:eBioscience (含Bender)

规格:100 ug

目录价:¥4188.00

市场价格:¥3559.80

会员价格:¥3476.04

金山科研平台,产品价格货期咨询微信:jinshanbio

Description: This mGI191E monoclonal antibody reacts with mouse Bcl-6, which is also known as B-cell lymphoma 6. A member of the POZ family of transcriptional repressors, Bcl-6 is expressed most abundantly in germinal center B cells, as well as in differentiating and activated B cells. This 79-kDa protein is essential for germinal center B cell proliferation and survival. Moreover, during B cell development, Bcl-6 plays an important role in promoting pre-B cell survival to enable the generation of a diverse B cell repertoire. Moreover, Bcl-6 is expressed constitutively in diffuse large B cell lymphomas (DLBCLs), Burkitt’s lymphoma, and non-Hodgkin’s lymphoma. Reports also suggest expression of Bcl-6 in CD4+ T follicular helper cells and memory T cells. Bcl-6 has been reported to be antagonized by Blimp-1.

Host Mouse
Isotype IgG1
Reactivity Mouse
Conjugate PE
Laser Blue Laser, Green Laser, Yellow-Green Laser
Excite 488 - 561 nm
Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis

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