货号:12-3059-41
品牌:eBioscience (含Bender)
规格:25 tests
目录价:¥1188.00
市场价格:¥1009.80
会员价格:¥986.04
金山科研平台,产品价格货期咨询微信:jinshanbio
Description: This NKTA255 monoclonal antibody reacts with human CD305, which is also known as leukocyte-associated Ig-like receptor (LAIR) 1. CD305 is a type I transmembrane glycoprotein that possesses an extracellular Ig-like domain and two intracellular ITIMs. CD305 is expressed on nearly all immune cells, including T, NK, and B cells, as well as monocytes, dendritic cells, eosinophils, basophils, and mast cells. In humans, this molecule is also expressed on CD34+ hematopoietic progenitor cells and thymocytes. Several isoforms of CD305 exist due to alternative splicing, and their expression may differ between cell types. As an inhibitory receptor, CD305 blocks cytokine-mediated signaling, cell proliferation, and apoptosis. Studies have also identified collagens as the ligands for CD305.The NKTA255 antibody has been reported to inhibit NK cytolytic activity.
Host |
Mouse |
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Isotype |
IgG1 |
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Reactivity |
Human |
---|
Conjugate |
PE |
---|
Laser |
Blue Laser, Green Laser, Yellow-Green Laser |
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Emit |
575 nm |
---|
Excite |
488 - 561 nm |
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Reported Applications |
Flow Cytometric Analysis |
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