eBioscience (含Bender)代理12-3007-42 Anti-Human CD300e (IREM-2) PE 100 tests；价格见Thermo同编号产品-试剂-金山科研平台

eBioscience (含Bender)代理12-3007-42 Anti-Human CD300e (IREM-2) PE 100 tests；价格见Thermo同编号产品

2025-06-25

货号：12-3007-42

品牌：eBioscience (含Bender)

规格：100tests

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio

Description: The monoclonal antibody UP-H2 recognizes human IREM-2 (immune receptor expressed in monocytic derived cells) also known as LMIR6, and unofficially CD300E and CD300LE. It is a member of the CMRF-35 family. This 34 kDa Ig-like containing receptor is an activating receptor and through it’s charged residues in the cytokplasmic domain interacts with ITAM containing adaptor proteins like DAP12. Expression is found exclusively on monocytes and myeloid DC’s. Expression may be transient as differentiation of monocytes leads to down regulation of IREM-2 yet expression is found on mature DCs. It has been also noted that myeloid cell lines such as THP-1 and U937 do not express IREM-2.In vitro addition of UP-H2 antibody either soluble or crosslinked stimulates monocytes.

Host	Mouse
Isotype	IgG1
Reactivity	Human
Conjugate	PE
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Emit	575 nm
Excite	488 - 561 nm
Reported Applications	Flow Cytometric Analysis

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