eBioscience (含Bender)代理11-5874-80 Anti-Mouse CD357 (GITR) FITC 25 ug；价格见Thermo同编号产品-试剂-金山科研平台

eBioscience (含Bender)代理11-5874-80 Anti-Mouse CD357 (GITR) FITC 25 ug；价格见Thermo同编号产品

2025-06-25

货号：11-5874-80

品牌：eBioscience (含Bender)

规格：25ug

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio

Description: The DTA-1 monoclonal antibody reacts with mouse GITR, Glucocorticoid-Induced TNFR family gene, also known as TNFRSF18. In naïve mice, GITR is expressed predominantly by CD4+CD25+ T regulatory cells (Treg) and by CD25+ CD4+ CD8- thymocytes. Stimulation of GITR with DTA-1 antibody abrogates Treg cell-mediated suppression. Although it does not deplete CD357 expressing cells in vivo, it has been shown to induce tumorogenesis. The removal of GITR-expressing Treg cells or the administration of DTA-1 resulted in organ specific autoimmune disease.

Host	Rat
Isotype	IgG2b, kappa
Reactivity	Mouse
Conjugate	FITC
Laser	Blue Laser
Excite	488 nm
Reported Applications	Flow Cytometric Analysis

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