货号：701258

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：EACH

目录价：￥4692.00

市场价格：￥4222.80

会员价格：￥4222.80

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 This purified ABfinity™ recombinant rabbit monoclonal antibody (mAb) recognizes Histone H3 [pS10] in human samples.ABfinity™ antibody characteristics include:• Validation in Western Blot, Immunofluorescence, Flow Cytometry and ChIP• Superior lot-to-lot consistency• Extremely high specificity and sensitivity• Recombinant rabbit monoclonal antibody• Specific for Histone H3 [pS10] Histone H3 is one of 5 histone proteins that is involved in the nucleosome core, around which DNA tightly wraps to form the chromatin structure in eukaryotic cells. Protruding from the globular nucleosome core, the N-terminal tail of histone H3 may undergo several different types of post-translational modifications. Histone H3 is known to be the most post-translationally modified of all histones; hence, it has a growing importance in the field of epigenetics, since its highly variant sequences and variable modification states are thought to play a role in the dynamic and long term regulation of genes that influence cellular processes. Mammalian cells have 3 known histone H3 sequence variants called Histone H3.1, Histone H3.2, and Histone H3.3. The sequences of these variants are highly conserved and differ only by a few amino acids. The ABfinity™ recombinant rabbit monoclonal antibody recognizes Histone H3 specifically at the phosphorylated serine at the 10th amino acid position.Exceptional Consistency Saves You Time and MoneyABfinity™ antibodies are produced by transfection of mammalian cells with heavy and light chain antibody cDNAs. This provides you with the highest consistency between lots, eliminating the need to revalidate your assays for each lot.High Specificity Means More Reliable DataThe proprietary recombinant technology employed in the production of ABfinity™ antibodies means you are assured of the greatest degree of reliability. Staining of nonspecific proteins is virtually eliminated while very high sensitivity is achieved. This antibody has been validated in Western Blot, Immunofluorescence, Flow Cytometry and ChIP.High Sensitivity Lets You Detect Low Levels of Target ProteinABfinity™ antibodies demonstrate much higher sensitivity than ordinary antibodies. Proteins expressed in low levels can be detected with high specificity allowing you to use less of your precious samples than with ordinary antibodies.Recombinant Rabbit IgG—Use Like Any Other IgG AntibodyAs with traditional IgG antibodies, gel electrophoresis of ABfinity™ antibodies produces a 150 kDa band under non-reducing conditions and 50 kDa and 25 kDa bands under reducing conditions.For Research Use Only.Not intended for any animal or human therapeutic or diagnostic use.Related Links:Learn more about the superior performance of ABfinity™ recombinant monoclonal antibodies.See Life Technologies' full line of ABfinity™ recombinant monoclonal antibodies. 规格

Reactivity:	Human
Validated Application:	Flow Cytometry,Immunofluorescence,Chromatin Immunoprecipitation,Western Blot
Host:	Rabbit
SubClass (Isotype):	IgG
Clonality:	Monoclonal
Clone ID:	9H12L10
Antibody Fragment:	Whole Antibody
Target Gene:	Histone H3 (pS10)
Gene ID:	8350
Gene Symbol:	HIST1H3A
Accession Number:	P68431
Label or Dye:	Unconjugated
Target Modification State:	Phospho
Form:	Liquid
Product Size:	100 µg
Buffer:	Phosphate buffered saline (PBS) with 0.09% sodium azide
Other Additives:	Sodium Azide Preservative
Shipping Condition:	Wet Ice

内容及储存 Store at 2-8°C for up to 1 month, -20°C for long-term storage. Avoid repeated freezing and thawing.