货号：701030

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：100 UG

目录价：￥4692.00

市场价格：￥4222.80

会员价格：￥4222.80

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 This purified ABfinity™ recombinant rabbit monoclonal antibody recognizes RANTES in human, mouse, and rat.ABfinity™ RANTES antibody characteristics include:• Excellent lot-to-lot consistency• Extremely high specificity and sensitivity• Recombinant rabbit IgG• Validation in Western blotSpecific for RANTESThe RANTES (regulated upon activation, normal T cell expressed and secreted) gene is one of the CC cytokine genes present on chromosome 17, clustered on q arm, and associated with the inflammatory response (1). It functions as a chemoattractant for blood monocytes, eosinophils, and memory T helper cells (2-3) and shows inhibition of replication/entry of various strains of HIV and SIV (4-6). RANTES (Ms) is encoded by the 20304 gene, also known as C-C motif chemokine 5.Exceptional Consistency Saves You Time and Money ABfinity™ antibodies are produced by transfection of mammalian cells with heavy and light chain antibody cDNAs. This provides you with the highest consistency between lots, eliminating the need to revalidate your assays for each lot.High Specificity Means More Reliable DataThe proprietary recombinant technology employed in the production of ABfinity™ antibodies means you are assured of the greatest degree of reliability. Staining of nonspecific proteins is virtually eliminated while very high sensitivity is achieved. Invitrogen has validated this antibody in Western blotting (Figure 1).High Sensitivity Lets You Detect Low Levels of Target ProteinABfinity™ antibodies demonstrate much higher sensitivity than ordinary antibodies. Proteins expressed in low levels can be detected with high specificity allowing you to use less of your precious samples than with ordinary antibodies.Recombinant Rabbit IgG--Use Like Any Other IgG AntibodyAs with traditional IgG antibodies, gel electrophoresis of ABfinity™ antibodies produces a 150kDa band under non-reducing conditions and 50kDa and 25kDa bands under reducing conditions.This product is for research use only. Not for use in diagnostic proceduresLearn more about the superior performance of ABfinity™ recombinant monoclonal antibodies See Invitrogen’s full line of ABfinity™ recombinant monoclonal antibodiesReferences(1) Schall, T.J. (1991). Biology of the RANTES/SIS cytokine family. Cytokine 3, 165-183.(2) Schall, T.J., Bacon, K., Toy, K.J., and Goeddel, D.V. (1990). Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 347, 669-671.(3) Schroder, J.M., Kameyoshi, Y., and Christophers, E. (1993). Platelets secrete an eosinophil-chemotactic cytokine which is a member of the C-C-chemokine family. Advances in experimental medicine and biology 351, 119-128(4) Cocchi, F., DeVico, A.L., Garzino-Demo, A., Arya, S.K., Gallo, R.C., and Lusso, P. (1995). Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. Science (New York, NY 270, 1811-1815.(5) Gauduin, M.C., Glickman, R.L., Means, R., and Johnson, R.P. (1998). Inhibition of simian immunodeficiency virus (SIV) replication by CD8(+) T lymphocytes from macaques immunized with live attenuated SIV. Journal of virology 72, 6315-6324.(6) Mavoungou, D., Poaty-Mavoungou, V., Akoume, M.Y., Ongali, B., and Mavoungou, E. (2005). Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor (IM28). Virology journal 2, 9. 规格

Reactivity:	Mouse
Validated Application:	Western Blot
Host:	Rabbit
SubClass (Isotype):	IgG
Clonality:	Monoclonal
Clone ID:	25H14L17
Antibody Fragment:	Whole Antibody
Target Gene:	Rantes
Gene ID:	20304
Gene Symbol:	CCL5
Accession Number:	P30882
Label or Dye:	Unconjugated
Purification:	Purified
Concentration:	1.5 mg⁄ml
Form:	Frozen
Mass:	100 µg
Neutralizing Antibody:	No
Product Size:	100 μg
Protein Family:	Chemokines & Receptors
Volume:	200 µl
Shipping Condition:	Approved for shipment on Wet or Dry Ice

内容及储存 2-8°C for up to 1 month, -20°C for long term storage. Avoid repeated freezing and thawing.