货号：700179

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：100 UG

目录价：￥4692.00

市场价格：￥4222.80

会员价格：￥4222.80

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 This purified ABfinity™ recombinant rabbit anti-CUL2 monoclonal antibody reacts to human, mouse and rat CUL2. Based on sequence identity and similarity, reactivity to primate, canine, and numerous other species is expected. Validated applications for CUL2 monoclonal antibody are Western blotting, flow cytometry, immunofluorescence, and immunohistochemistry. Applications: Validated applications for this rabbit anti-CUL2 monoclonal antibody are Western blotting, flow cytometry, immunofluorescence, and immunohistochemistry. Host species and isotype: The host species and isotype of the CUL2 monoclonal antibody is rabbit IgG. Clone ID of monoclonal antibody (mAb): The rabbit anti-CUL2 monoclonal antibody clone is 50H17L12. Reactivity: Rabbit anti-CUL2 monoclonal antibody detects human, mouse and rat CUL2. Based on sequence homology resactivity to primate, canine, and numerous other species is expected. Product size: Rabbit anti-CUL2 monoclonal antibody is available in a 100 µg pack size. In yeast, proteolysis of G1 cell cycle regulatory proteins is controlled by a ubiquitin ligase formed by three subunits: Cdc53 (also known as CulA), Skp1, and one of many F-box proteins. A family of human cullin genes homologous to the S. cerevisiae cdc53 gene has been identified (cul1, 2, 3, 4a, 4b, and 5). In humans, Cul2 is part of the ECS (Elongin B/C-Cul2/Cul5-SOCS-box protein) complex which contains the Cullin-RBX module. human Cul2 does not associate with Skp1 or Skp2. Instead, it forms a complex with an inactive transcriptional elongation complex, SIII, formed by three subunits: Elongin C, Elongin B and VHL. The Cul2-Rbx1 module specifically interacts with the VHL box. Elongin C shows homology with Skp1, and Elongin B with ubiquitin. In its active form, SIII does not contain VHL, but rather contains an F box protein, Elongin A. 规格

Reactivity:	Human,Mouse,Rat
Validated Application:	Flow Cytometry,Immunofluorescence,Western Blot,Immunohistochemistry
Host:	Rabbit
SubClass (Isotype):	IgG
Clonality:	Monoclonal
Clone ID:	50H17L12
Antibody Fragment:	Whole Antibody
Target Gene:	Cul-2
Gene ID:	8453
Accession Number:	Q13617
Label or Dye:	Unconjugated
Purification:	Affinity Purified
Concentration:	0.5 mg⁄ml
Color:	Unconjugated
Form:	Liquid
Neutralizing Antibody:	No
Platform:	Fluorescence Microscope,Flow Cytometer,Confocal Microscope
Product Size:	100 µg
Quantity:	1
Volume:	200 µl
Shipping Condition:	Wet Ice

内容及储存 2-8°C for up to 1 month, -20°C for long term storage. Avoid repeated freezing and thawing.