货号：700013

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：100 UG

目录价：￥4692.00

市场价格：￥4222.80

会员价格：￥4222.80

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 This purified ABfinity™ recombinant rabbit anti-FAK [pY576] monoclonal antibody is specific to human FAK [pY576] and does not recognize non-phosphorylated FAK protein. Based on sequence similarity, reactivity to chimpanzee, rhesus monkey, macaque, mouse, rat, chicken, Xenopus, and zebrafish is expected. This rabbit anti-FAK [pY576] monoclonal antibody can be used in Immunofluorescence and Flow Cytometry.Antibody Specifications:• Applications: The validated applications for this rabbit anti-FAK [pY576] monoclonal antibody are Immunofluorescence and Flow Cytometry.• Host Species and Isotype: The host species and isotype of the FAK [pY576] antibody is rabbit IgG.• Clone ID of Monoclonal Antibody (mAb): The rabbit anti-FAK [pY576] monoclonal antibody clone is 2H74L24.• Reactivity: Reacts to human FAK [pY576].• Product Size: Rabbit anti-FAK [pY576] monoclonal antibody is available in a 100 µg size. Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that acts as a substrate for Src and is a key element of integrin signaling. FAK plays a central role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle. Regulatory mechanisms of FAK include phosphorylation at multiple tyrosine and serine residues. Increased FAK tyrosine phosphorylation occurs upon integrin engagement with fibronectin. The phosphorylation by Src of tyrosines 576 and 577 in the activation loop results in maximal activity of FAK. However, the two sites appear to be differentially regulated. 规格

Reactivity:	Human
Validated Application:	Flow Cytometry,Immunofluorescence
Host:	Rabbit
SubClass (Isotype):	IgG
Clonality:	Monoclonal
Clone ID:	2H74L24
Antibody Fragment:	Whole Antibody
Target Gene:	FAK [pY576]
Gene ID:	5747
Accession Number:	Q05397
Label or Dye:	Unconjugated
Target Modification State:	Phospho
Purification:	Affinity Purified
Concentration:	0.5 mg⁄ml
Color:	Unconjugated
Neutralizing Antibody:	No
Product Size:	100 µg
Protein Family:	Kinases & Inhibitors,Extracellular Matrix & Cell Adhesion
Quantity:	1 each
Volume:	200 µl
Research Category:	Signal Transduction,Extracellular Matrix & Cell Adhesion
Shipping Condition:	Approved for shipment on Wet or Dry Ice

内容及储存 2-8°C for up to 1 month, -20°C for long term storage. Avoid repeated freezing and thawing.