货号：PA516793

品牌：Pierce

规格：EA

目录价：询价

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GLUT1 Antibody (PA5-16793) Formalin-fixed, paraffin-embedded human squamous cell carcinoma stained with Glut-1 antibody using peroxidase-conjugate and AEC chromogen. Note membrane staining of tumor cells.

Details
Tested species reactivity	Human,Rat
Published species reactivity	Rat,Human,Mouse
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	A synthetic peptide derived from C-terminal of human GLUT-1
Conjugate	Unconjugated
Form	Liquid
Concentration	0.2 mg/ml
Purification	Affinity chromatography
Storage buffer	PBS, pH 7.6, with 0.2% BSA
Contains	15mM sodium azide
Storage Conditions	4° C

Tested Applications	Dilution*
Immunofluorescence (IF)	Assay Dependent
Immunohistochemistry (Paraffin) (IHC (P))	1:200
Western Blot (WB)	2-4 ug/ ml

^*Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

Published Applications
Western Blot (WB)	See 4 publications below
Immunohistochemistry (Paraffin) (IHC (P))	See 1 publications below
Immunohistochemistry (IHC)	See 14 publications below
Immunocytochemistry (ICC)

Product Specific Information

PA5-16793 targets GLUT-1 in IHC (P), WB, and IF applications and shows reactivity with Human and Rat samples. The PA5-16793 immunogen is a synthetic peptide derived from C-terminal of human GLUT-1.

Background/Target Information

Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling. GLUT-1 is detectable in many human tissues including those of the colon, lung, stomach, esophagus, and breast. GLUT-1 immunoreactivity in some cancers, including trans carcinoma of the urinary bladder, has been associated with aggressive behavior.