货号:44429G
品牌:ThermoFisher /Invitrogen/ Gibco/ ABI
规格:7VIALSBIOSOURCE(TM)
目录价:¥5540.00
市场价格:¥4986.00
会员价格:¥4986.00
金山科研平台,产品价格货期咨询微信:jinshanbio
描述
The purified, unconjugated antibodies in rabbit anti-JAK/STAT antibody Sample Pack are specific to human, mouse, rat, swine and monkey JAK/STAT. STATs (signal transducers and activators of transcription) are transcription factors that play important roles in numerous cellular processes including immune responses, cell growth, differentiation, cell survival, apoptosis and oncogenesis. Validated application for antibodies in rabbit anti-JAK/STAT antibody Sample Pack is Western blot.• Applications: Validated application for antibodies in rabbit anti-JAK/STAT antibody Sample Pack is Western blot. Please see the manual for recommended usage for this antibody.
• Reactivity: Antibodies in rabbit anti-JAK/STAT antibody Sample Pack detect human, mouse, rat, swine and monkey JAK/STAT. Please see the manual for species reactivity of each antibody.
• Product size: The JAK/STAT Antibody Sample Pack is available in a 7-vial pack size.STATs (signal transducers and activators of transcription) are transcription factors that play important roles in numerous cellular processes including immune responses, cell growth, differentiation, cell survival, apoptosis and oncogenesis. Binding of a growth factor or cytokine to its cell surface receptor results in the activation of the Janus kinases (JAK1 and JAK2), which, in turn, are able to phosphorylate the STAT proteins on critical tyrosine residues that then facilitate STAT protein dimerization. STAT dimers then translocate to the nucleus where they can activate the transcription of STAT-responsive genes. Serine phosphorylation of STAT proteins appears to be required for maximum transcriptional activity. More recently, tyrosine phosphorylation of STAT3 has been shown to also involve the Src protein tyrosine kinase, thereby adding to the complexity of STAT protein regulation. The JAK/STAT PSSA Sampler Pack allows one to readily study selective phosphoregulation of multiple sites along proteins involved in the JAK/STAT signaling pathway.
详细说明
常用规格
Reactivity: |
Rat,
Human,
Mouse
|
Validated Application: |
Western Blot
|
Host: |
Rabbit
|
Clonality: |
Polyclonal
|
Clone ID: |
Sampler Pack
|
Target Gene: |
JAK/STAT
|
Label or Dye: |
Unconjugated
|
Target Modification State: |
Phospho
|
Product Size: |
7 vials
|
Research Category: |
Signal Transduction
|
Purity or Quality Grade: |
Azide Free
|
Shipping Condition: |
Approved for shipment on Wet or Dry Ice
|
Regulatory Statement: |
For Research Use Only. Not for use in diagnostic procedures.
|
内容和储存
Store in freezer (-5 to -30°C).
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