货号:180215
品牌:ThermoFisher /Invitrogen/ Gibco/ ABI
规格:1 ML
目录价:¥5234.00
市场价格:¥4710.60
会员价格:¥4710.60
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描述
Synucleins (α, β, and γ) are a family of cytoplasmic proteins found predominantly, and abundantly, in the brain with cellular distribution concentrated in presynaptic nerve terminals, primarily near vesicles. Synucleins are thought to be involved in neuronal plasticity, synaptic function, and neurodegenerative disease. α-Synuclein (~18 kDa) is abundant in Lewy Bodies in sporadic Parkinson's Disease (PD) and Dementia with Lewy Bodies (DLB). It has been reported that the NAC fragment from α-synuclein is a major component of amyloid plaques in Alzheimer's Disease. LB509 reacts with α-synuclein but not SM-synuclein. Reactivity has not been observed with γ-synuclein. Positive tissue: Parkinson's disease tissue.Clone/PAD: LB509Immunogen: Lewy Bodies purified from patients suffering dementia with Lewy BodiesSpecificity: α-SynucleinReactivity: HumanApplications: Immunohistochemistry (FFPE)Pretreatment: Epitope Retrieval: Not required, Enzyme Digestion: Not requiredExpected Staining Pattern: Cytoplasmic
规格
Reactivity: |
Human |
Validated Application: |
Immunohistochemistry (FFPE) |
Host: |
Mouse |
SubClass (Isotype): |
IgG1, kappa |
Clonality: |
Monoclonal |
Target Gene: |
alpha-Synuclein |
Gene ID: |
6622 |
Label or Dye: |
Unconjugated |
Dilution: |
Concentrate Antibody |
Product Size: |
1 mL |
Shipping Condition: |
Wet Ice |
内容及储存
Store in refrigerator (2–8°C).
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