货号：11880H08H50

品牌：ThermoFisher /Invitrogen/ Gibco/ ABI

规格：50UG

目录价：￥5114.00

市场价格：￥4602.60

会员价格：￥4602.60

金山科研平台，产品价格货期咨询微信：jinshanbio 描述 Manufactured by Sino Biological (China); Distributed by Life Technologies. Cluster of Differentiation 19 (CD19) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in analysis of protein structure the study of protein-protein interactions, and cell biology research applications. It can also be used as an immunogen, or as a protein standard.This recombinant protein is expressed from a DNA sequence encoding the extracellular domain (Met 1-Lys 291) of human CD19 (AAB60697) fused to a polyhistidine tag at the C-terminus.N-terminal Sequence Analysis: Pro 20.Activity: measured by its binding ability in a functional ELISA . Immobilized human CD19 at 2 µg/mL(100 µL/well) has been shown to bind biotinylated human CD9 with a linear range of 0.032-0.8 µg/mL.Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween®-80.Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.Expiration Date: expires one year from date of receipt when stored as instructed.BackgroundCluster of Differentiation 19 (CD19), is a single-pass type I membrane protein which contains two Ig-like C2-type (immunoglobulinlike) domains. CD19 forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells. It interacts with VAV. It interacts with GRB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378. CD19 also interacts with PLCG2 when phosphorylated on Tyr-409. CD19 is an important pan B cell marker and co-stimulatory protein in humans and mice. CD19 is a hallmark differentiation antigen of the B cell lineage and positively regulates antigen receptor signal transduction in mature B cells. CD19 defines signaling thresholds for the Ag receptor as well as other cell surface receptors that regulate B lymphocyte selection, activation, and differentiation. Defects in CD19 are a cause of hypogammaglobulinemia.You may also be interested in the following CD19 products: Cell IsolationPrimary AntibodiesGene Expression Assays 规格

Form:	Lyophilized
Purity:	≥ 90% by SDS-PAGE
Gene ID:	930
Species:	Human
Expression:	Mammalian
Gene Symbol:	CD19
Gene Aliases:	B4, MGC12802
Product Size:	50 µg
Protein Form:	Truncated,Recombinant,Cell Surface Protein
Protein Family:	CD Proteins
Endotoxin Level:	< 1 EU/µg
Protein Subtype:	Other Proteins
Molecular Weight:	31.6 kDa
Research Category:	Immunology
Protein Tag or Fusion:	His Tag
Validated Application:	Assay Standard
Shipping Condition:	Room Temperature

内容及储存 Store at -20 to -70 °C