货号：644493

品牌：BD Pharmingen

规格：

目录价：询价

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Catalog Number

644493

Brand

BD Horizon™

Name

FMC7

Size

100Tests

RegulatoryStatus

RUO (GMP)

Clone

FMC7

Format

V450

Isotype

IgM, κ

W.S. No

none

W.B. Positive Control

none

Molecular Weight

none

Reactivity

QC Testing : Human

Applications

Flow cytometry

- Routinely Tested

Clone - Description

FMC7 recognizes a 105-kd membrane glycoprotein expressed on a subset of B lymphocytes.More than 50% of the peripheral B lymphocytes of normal adults carry the FMC7 antigen at variable density. FMC7-positive B cells are more mature, and they include the subpopulation that responds in vitro to mitogens or antigens. The FMC7 antigen is found on B-cell malignancies of most differentiated stages, such as mantle cell lymphoma, but not in most cases of chronic lymphocytic leukemia (CLL).