货号：561009

品牌：BD Pharmingen

规格：1EA

目录价：￥2428.00

市场价格：￥1529.64

会员价格：￥1335.40

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Catalog Number

561009

Brand

BD Pharmingen™

Name

CD123

Alias

IL-3 Receptor α chain

Size

25Tests

RegulatoryStatus

RUO

Clone

9F5

Format

PE-Cy™ 5

Isotype

IgG₁, κ

W.S. No

VI C-67

W.B. Positive Control

none

Strain Host

BALB/c

Reactivity

QC Testing : Human

Applications

Flow cytometry

- Routinely Tested

Clone - Description

CD123 (Anti–IL-3Ra) binds to the a-chain of the interleukin-3 receptor (IL-3Ra). It selectively recognizes COS cells that have been transfected with IL-3Ra. Clone 9F5 does not block IL-3 binding to the receptor.CD123 is expressed on a subset of peripheral blood dendritic cells, on a subset of progenitor cells, monocytes, eosinophils, and basophils. Neutrophils show IL-3Ra expression when they are cultured with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not when freshly isolated. As IL-3 stimulates the production of hematopoietic cells, such as megakaryocytes, erythroid cells, and B cells, it is assumed that these lineages can also express IL-3Ra.