货号：558455

品牌：BD Pharmingen

规格：1EA

目录价：￥4107.00

市场价格：￥2587.41

会员价格：￥2258.85

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The monoclonal alloantibody X54-5/7.1 reacts with FcgRI (CD64) encoded by the more common Fcgr1a and Fcgr1b alleles. The alloantigens generated by the Fcgr1a and Fcgr1b alleles, have been confirmed positive in mouse strains BALB/c and C57BL/6 and reported positive in strains 129, A, AKR, ALR, BUB, C3H, C57BL/10, C57BLKS, C57BR, C58, CBA, CE, DBA/2, HRS, MRL, NON, NZB, NZO, NZW, PL, SJL, ST, SWR. The a and b alloantigens have been reported negative in mouse strains ABH, NOD. CD64, a key receptor in the development of immune responses, has a dual role as a low affinity receptor for IgG3 and high affinity receptor for IgG2a linking innate and adaptive immunities. CD64 mediates endocytosis, phagocytosis, antibody-dependent cellular toxicity, cytokine release and superoxide generation. CD64 is expressed largely on macrophages and dendritic cells. For more information regarding clone X54-5/7.1 and the alloantigens it recognizes, please refer to the technical data sheet.

Catalog Number

558455

Brand

BD Pharmingen™

Name

CD64 a and b Alloantigens

Concentration

0.2 mg/ml

Size

0.1mg

RegulatoryStatus

RUO

Clone

X54-5/7.1

Format

PE

Isotype

IgG₁, κ

W.B. Positive Control

none

Immunogen

Mouse CD64 a Alloantigen

Strain Host

NOD/Lt

Reactivity

QC Testing : Mouse

Applications

Flow cytometry

- Routinely Tested