货号：558364

品牌：BD Pharmingen

规格：100ug

目录价：￥9240.00

市场价格：￥5821.20

会员价格：￥5082.00

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The caveolins are a family of transmembrane proteins that are required for the structural integrity and functions of non-clathrin membrane invaginations (caveolae) on the inner surface of the plasma membrane. The intracellular functions of caveolae include roles in cholesterol homeostasis, signal transduction, and vesicle transport. Caveolins 1 and 2 form hetero-oligomers in the endoplasmic reticulum, Golgi complex and trans-Golgi-derived transport vesicles in most tissues. The highest levels of these complexes are found in adipocytes, fibroblasts, and endothelial, epithelial, and smooth muscle cells. Upon phosphorylation at tyrosine 19 or 27, caveolin 2 dissociates from caveolin 1, and the two phosphorylated forms of caveolin 2 localize to distinct areas of the cell. There are reports that internalization of caveolae may be regulated by tyrosine phosphorylation of caveolin 2.

Catalog Number

558364

Brand

BD Pharmingen™

Name

Caveolin 2 (pY27)

Concentration

0.25 mg/ml

Size

0.1mg

RegulatoryStatus

RUO

Clone

40/Caveolin 2

Format

Purified

Isotype

IgG₁, κ

W.B. Positive Control

none

Molecular Weight

20 kDa

Immunogen

Phosphorylated Human Caveolin 2

Strain Host

BALB/c

Reactivity

QC Testing : Human

Applications

Fluorescence microscopy	- Reported
Immunohistochemistry-formalin (antigen retrieval required)	- Tested During Development