BD Pharmingen代理555966 Hu NKB1 FITC DX9 100Tst冷藏2-8°C-试剂-金山科研平台

BD Pharmingen代理555966 Hu NKB1 FITC DX9 100Tst冷藏2-8°C

2025-06-21

货号：555966

品牌：BD Pharmingen

规格：1EA

目录价：￥3898.00

市场价格：￥2455.74

会员价格：￥2143.90

金山科研平台，产品价格货期咨询微信：jinshanbio

Catalog Number: 555966
Brand: BD Pharmingen™
Name: NKB1
Alias: KIR
Size: 100Tests
RegulatoryStatus: RUO

Clone

DX9

Format

FITC

Isotype

IgG₁, κ

Reactivity

QC Testing : Human

Applications

Flow cytometry

- Routinely Tested

Clone - Description

Anti-human killer inhibitory receptor (KIR), NKB1, (Anti-Hu KIR [NKB1]) recognizes a 70-kDa glycoprotein that is a member of the p58/NK-associated transcript (NKAT) family of class I receptors. KIR (NKB1) is an MHC class I receptor that inhibits NK cell–mediated cytotoxicity on target cells that express HLA-B molecules of the Bw4 serotype, but it does not affect recognition of HLA-A or HLA-C antigens. KIR (NKB1)-mediated inhibition is abrogated by binding of Anti-Hu KIR (NKB1). Anti-Hu KIR (NKB1) also regulates T-cell activation initiated through the T-cell antigen receptor (TCR) complex. KIR (NKB1) is expressed on a subset of human NK cells (CD3^-/CD56⁺), NK cell clones, and a subset of human T lymphocytes.

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