货号：554300

品牌：BD Pharmingen

规格：100ug

目录价：￥5770.00

市场价格：￥3635.10

会员价格：￥3173.50

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Catalog Number

554300

Brand

BD Pharmingen™

Name

c-erbB-2

Concentration

0.5 mg/ml

Size

100µg

RegulatoryStatus

RUO

Clone

9G6

Format

Purified

Isotype

IgG₁

W.B. Positive Control

none

Immunogen

Recombinant human c-erbB-2

Reactivity

QC Testing : Human

Applications

Flow cytometry	- Reported
Immunohistochemistry-formalin (antigen retrieval required)	- Routinely Tested
Immunohistochemistry-frozen	- Routinely Tested
Immunoprecipitation	- Reported

Clone - References

1. Hesketh, Robin. 1994. The Oncogene Handbook. Aademic Press (N.Y., N.Y). pp. 485-509.2. Hancock, M.C., B.C. Langton, T. Chan, P. Toy, J.J. Monahan, R.P. Mischak and L.K. Shawver. 1991. A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diamminedichloroplatinum against human breast and ovarian tumor cell lines. Cancer Res. 51:4575-4589.3. Carraway, K.L. and L.C. Cantley. 1994. A neu acquaintance of ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling. Cell 78:5-8. Van De Vijver, M.J., J.L. Peterse, W.J. Mooi, P. Wisman, J. Lomans, O. Dalesio and R. Nusse. 1988. Neu-protein overexpression in breast cancer: Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer. New England J. Med 1319:1239-1244.4. Stal, O., S. Sullivan, X.F. Sun, S. Wingren and B. Nordenskjold. 1994. Simultaneous analysis of c-erbB-2 expression and DNA content in breast cancer using flow cytometry. Cytometry 16:160-168.5. Penault-Llorca, F., J. Adelaide, G. Houvenaeghel, J. Hassoun, D. Birnbaum and J. Jacquemier. 1994. Optimization of immunohistochemical detection of ErbBB2 in human breast cancer. J. Pathol. 173:65-75.6. Schwechheimer, K., R.M. Laufle, W. Schmahl, M. Knodlseder, H. Fischer and H. Hofler. 1994. Expression of neu/c-erb-2 in human brain tumors. Human Pathol. 25:772-80.7. Rubin, S.C., C.L. Finstad, G.Y. Wong, L. Almadrones, M. Plante and K.O. Lloyd. Prognositic significance of HER-2/neu expression in advanced epithelial ovarian cancer: a multivariate analysis. Am. J. of Obst. and Gyn. 168:162-169. 8. Singleton, T.P., G.A. Niehans, F. Gu, C.E. Litz, K. Hagen, Q. Qiu, D.T. Kiang and J.G. Strickler. 1992. Detection of c-erbB-2 activation in paraffin-embedded tissue by immunohistochemistry. Human Pathol. 10:1141-1150.

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