货号：ABE184

品牌：Merck Millipore

规格：100Ug

目录价：￥4899.00

市场价格：￥4164.15

会员价格：￥3919.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Fox2 Antibody | ABE184 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Molecular Weight: ~48 kDa observed. Alternative splicing can result in up to 9 isoforms at various molecular weights. Uncharacterized bands between ~60-80 kDa have been observed in some cell lysates. View All» Immunogen: MBP-tagged recombinant protein corresponding to mouse Fox2. View All» Background Information: Fox2, also referred to as RNA binding protein fox-1 homolog 2, is an RNA binding protein involved in the regulation of tissue-specific alternative splicing. This protein interacts with the ER-alpha N-terminal activation domain, and contains a highly conserved RRM (RNA recognition motif), which associates with 5'-UGCAUGU-3' elements. This protein has been demonstrated to regulate alternative splicing of tissue specific exons and differentially spliced exons during erythropoiesis. View All» Species Reactivity:

• Mouse

• Human

• Rat
  View All» Species Reactivity Note: Demonstrated to react with Human, Mouse, and Rat. Other homologies: Bovine (98% sequence homology), Canine (98% sequence homology), Equine (98% sequence homology). View All» Application Notes: Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected Fox2 in human cerebellum tissue.Immunocytochemistry Analysis: 1 µg/mL from a representative lot detected Fox2 in A431 cells. View All» Control: C2C12 cell lysate View All» Quality Assurance: Evaluated by Western Blot in C2C12 cell lysate.Western Blot Analysis: 50 ng/mL of this antibody detected Fox2 in 10 µg of C2C12 cell lysate. View All» Purification Method: Affinity purified View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q8BP71 View All» Entrez Gene Number: NP_444334 View All» Gene Symbol:
  • Rbfox2

  • Fox2, Fxh

  • Hrnbp2

  • Rbm9
    View All» Alternate Names:
    • RNA binding protein fox-1 homolog 2

    • Fox-1 homolog B

    • Fox-1 homolog Fxh

    • Hexaribonucleotide-binding protein 2

    • RNA-binding motif protein 9

    • RNA-binding protein 9
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Immunohistochemistry (Paraffin)

      • Immunocytochemistry

      • Western Blotting
        View All» UniProt Summary: FUNCTION: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. Seems to act as a coregulatory factor of ER-alpha.SUBUNIT STRUCTURE: Interacts with ER-alpha N-terminal activation domain.SUBCELLULAR LOCATION: Nucleus. Cytoplasm. View All» Product Name: Anti-Fox2 View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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